A few years later, in 2024, researchers in multiple labs were horrified to notice toxic batches of agar for reasons as yet unclear. After they observed a worrying lack of microbial growth (impeding their ability to carry out basic experiments), they switched to different agar suppliers, and their results improved.
The primary signal is desiredSize on the controller. It can be positive (wants data), zero (at capacity), negative (over capacity), or null (closed). Producers are supposed to check this value and stop enqueueing when it's not positive. But there's nothing enforcing this: controller.enqueue() always succeeds, even when desiredSize is deeply negative.
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